Recommended points from a registered dietitian
Registered Dietitian
Yurie Ando

What is Nattokinase

Nattokinase is a potent enzyme extracted from natto, a traditional Japanese food made from fermented soybeans. This enzyme is widely known for its ability to help dissolve blood clots, supporting cardiovascular health and maintaining healthy blood pressure.
Kawashimaya's Nattokinase Capsule + DHA/EPA combines 2400 FUs of Nattokinase (per 2 capsules), with DHA, EPA, vitamin E, and folic acid to help promote overall wellness and support your health every day.
Our capsules are made using non-genetically modified soybeans, and we use plant-based soft capsules for easy consumption. The product is gluten-free and produced in a GMP-certified facility in Japan. We’ve removed vitamin K2, ensuring no interaction with medications, and the product has no natto smell, making it suitable for everyone. It’s also Muslim-friendly.
Product Specialty

We are pleased to offer this exceptional product with many good points that can support your health and lifestyle.
Contains 2400 FUs + DHA/EPA (per 2 Capsules)
DHA and EPA are essential omega-3 fatty acids found in fish. These cannot be produced by the body, so they must be obtained through diet. They support brain function and cardiovascular health, playing a key role in cell communication.
In addition, our formula contains Vitamin E (alpha-tocopherol), which helps protect your body from oxidative stress, and folic acid, which supports healthy blood circulation by reducing homocysteine levels.
Non-GMO Soybeans Used
We use only high-quality, non-genetically modified soybeans to ensure purity and potency in every capsule.
Plant-Based Soft Capsules Used
Our nattokinase capsules are easy to swallow and 100% plant-based, offering a sustainable option for health-conscious consumers.
Gluten-Free
This product is tested for gluten content in the ingredient and the result came as “gluten-free.”
Manufactured by a GMP-Certified Factory
The manufacturing factory adheres to Good Manufacturing Practice, ensuring a product that you can rely on for both quality and safety.
Muslim-Friendly Ingredients
Although this product is not halal-certified yet, the ingredients have been inspected by the Japan Halal Association and deemed as Muslim Friendly. This means it has no animal-origin materials and doesn't contain alcohol.
100% Made in Japan
Crafted in Japan, where natto has been a cherished part of the diet for centuries, ensuring expert production of high-quality nattokinase.
Get Nattokinase Conveniently

This supplement is ideal for individuals who dislike the smell or taste of natto but still want to get the benefits of nattokinase. With no natto odor, it's a hassle-free way to support your health.
Nattokinase, which is contained in the sticky part of natto, is weak against acid. Therefore, even if you eat a lot of natto, the active ingredients do not reach deep into your body. Furthermore, consuming excessive natto poses a risk of affecting your purine levels.
Additionally, the zip-lock packaging is small enough to bring on a trip, making it a travel-friendly supplement.
Just 2 Capsules per Day

Simply take two capsules a day to promote smooth and healthy blood flow as part of your wellness routine.
Taking two Nattokinase capsules per day provides the same amount of nattokinase as 120 grams of natto (about three packs of natto), making it a more efficient and convenient option.
Each serving provides 2400 FUs, which is higher than the daily recommended amount of 2000 FUs set by the Japan Nattokinase Association.
Whether you're looking to support heart health or improve circulation, this supplement is a convenient and effective choice, backed by both traditional Japanese practices and modern science.
Additional Health Benefits

Our nattokinase capsules are enriched with more nutrients below:
● Omega-3s from DHA & EPA
These essential fatty acids are known for their role in maintaining heart health, brain function, and supporting overall wellness. Sourced with care, they complement Nattokinase to promote a healthy lifestyle.
● Antioxidant Protection with Vitamin E
Vitamin E helps protect cells from oxidative stress, supporting your body’s natural defenses and vitality.
● Folic Acid for Everyday Health
Folic acid supports red blood cell formation and overall energy metabolism, essential for maintaining your day-to-day wellness.
Q&A About Nattokinase
First of all, what is nattokinase?
Nattokinase is an enzyme derived from natto. It is known for its ability to dissolve blood clots and reduce the risk of stroke and other cardiovascular issues.
What is the unit "FU" of nattokinase?
"FU" stands for fibrinolytic units, a measure of the enzyme's ability to break down fibrin (blood clots). The higher the FU value, the greater the enzyme’s activity.
Is it okay to take this with medication?
Nattokinase is a food supplement, and it is generally safe to take with medications. However, if you are taking prescribed medicine or undergoing medical treatment, please consult your doctor before adding any supplements to your diet. Our product is free from vitamin K, which could interact with blood-thinning medications.
I am pregnant. Is it safe to take this?
If you are pregnant or breastfeeding, please consult with your healthcare provider before using this supplement.
I have a food allergy. Is it okay to bring this?
Please check the ingredients list carefully. This product contains soy-based ingredients, so if you are allergic to soy, it’s best to avoid this product.
Has Nattokinase been tested for mercury?
Yes, we have tested for heavy metals and arsenic, and our product is free from harmful levels of these substances.
Product Detail | |
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Product Name | Nattokinase Capsule + DHA/EPA |
Ingredients | DHA/EPA enriched refined fish oil (domestic production), starch, natto bacteria culture extract powder, reduced syrup / glycerin, carrageenan (derived from seaweed), emulsifier, vitamin E, vitamin B1, vitamin B6, vitamin B12, and folic acid. |
Allergen | Soybeans |
Content | 60g (1 capsule weight 455mg, with 300mg active ingredients per capsule × approximately 120 capsules) |
Place of Production | Japan |
Storage Instructions | Store in a cool, dark place away from direct sunlight, high temperatures, and humidity. If stored in a refrigerator, keep humidity between 10~20% as a guideline. |
Daily Dosage | Take 2 capsules per day with water or warm water as a guideline. |

Impotant Points Before Consumption
・Depending on your constitution or physical condition, this product may not be suitable for you. In that case, please refrain from using it.
・If you have a food allergy, please refer to the ingredients list before consuming.
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Although the product name is "Nattokinase," it does not have a strong smell like natto, and since it is easy to swallow and only requires two tablets a day, I found it easy to continue taking it.